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Near real-time MRI of interstitial laser photocoagulation of in vivo rat liver

CLEMENCE, M; ROBERTS, HRS; PALEY, M; BUONACCORSI, G; HALLCRAGGS, MA; BOWN, SG; LEES, WR; (1994) Near real-time MRI of interstitial laser photocoagulation of in vivo rat liver. In: MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE. (pp. 299 - 302). CHAPMAN HALL LTD

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Abstract

Magnetic resonance imaging (MRI) is showing considerable promise as a monitor for interventional procedures. Laser surgery is ''MRI compatible,'' and temperature-sensitive imaging techniques can be usefully applied to these procedures. We have been investigating T-1-derived temperature-dependent imaging as a monitor for interstitial laser photocoagulation (ILP) in rat liver. In vitro experiments suggested that temperature calibration may be achieved. We have investigated ILP in vivo using short TR spin-echo imaging sequences taking one set of images every 30 s during and after the procedure. Our results in vivo suggest that this simple model may be inadequate for temperature mapping as the biological reaction to the ILP is on a similar time scale to that of the procedure. Nonetheless, MRI shows well-defined, repeatable signal changes that can be related to histological borders.

Type: Proceedings paper
Title: Near real-time MRI of interstitial laser photocoagulation of in vivo rat liver
Event: 1st Nottingham Symposium on Magnetic Resonance Imaging
Location: NOTTINGHAM, ENGLAND
Dates: 1994
Keywords: MRI, LASER SURGERY, ILP, REAL-TIME, RAT LIVER, TEMPERATURE
UCL classification: UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of) > Research Department of General Surgery
URI: http://discovery.ucl.ac.uk/id/eprint/62313
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