CLEMENCE, M and ROBERTS, HRS and PALEY, M and BUONACCORSI, G and HALLCRAGGS, MA and BOWN, SG and LEES, WR (1994) Near real-time MRI of interstitial laser photocoagulation of in vivo rat liver. In: MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE. (pp. 299 - 302). CHAPMAN HALL LTD
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Magnetic resonance imaging (MRI) is showing considerable promise as a monitor for interventional procedures. Laser surgery is ''MRI compatible,'' and temperature-sensitive imaging techniques can be usefully applied to these procedures. We have been investigating T-1-derived temperature-dependent imaging as a monitor for interstitial laser photocoagulation (ILP) in rat liver. In vitro experiments suggested that temperature calibration may be achieved. We have investigated ILP in vivo using short TR spin-echo imaging sequences taking one set of images every 30 s during and after the procedure. Our results in vivo suggest that this simple model may be inadequate for temperature mapping as the biological reaction to the ILP is on a similar time scale to that of the procedure. Nonetheless, MRI shows well-defined, repeatable signal changes that can be related to histological borders.
|Title:||Near real-time MRI of interstitial laser photocoagulation of in vivo rat liver|
|Event:||1st Nottingham Symposium on Magnetic Resonance Imaging|
|Keywords:||MRI, LASER SURGERY, ILP, REAL-TIME, RAT LIVER, TEMPERATURE|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)|
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of) > Research Department of General Surgery
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