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STATISTICAL BASIS FOR THE DETERMINATION OF OPTICAL PATHLENGTH IN TISSUE

ARRIDGE, SR; HIRAOKA, M; SCHWEIGER, M; (1995) STATISTICAL BASIS FOR THE DETERMINATION OF OPTICAL PATHLENGTH IN TISSUE. PHYS MED BIOL , 40 (9) 1539 - 1558.

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Abstract

In this paper we show how to derive the mean and variance of the transilluminated signal obtained in models of light propagation in tissue, based both on a stochastic Monte Carlo method and on a deterministic diffusion approximation. The theoretical treatment of the Monte Carlo model applies only to integrated intensity measurements, whereas the diffusion approximation gives an estimator for the time-dependent case as well. We present results that show the accurate prediction of Monte Carlo statistics, and propose that the diffusion approximation is therefore a suitable mechanism for incorporating noise into modelling procedures.

Type: Article
Title: STATISTICAL BASIS FOR THE DETERMINATION OF OPTICAL PATHLENGTH IN TISSUE
Keywords: MODEL, SCATTERING, ABSORPTION, LIGHT
UCL classification: UCL > School of BEAMS > Faculty of Engineering Science
UCL > School of BEAMS > Faculty of Engineering Science > Computer Science
URI: http://discovery.ucl.ac.uk/id/eprint/61281
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