STATISTICAL BASIS FOR THE DETERMINATION OF OPTICAL PATHLENGTH IN TISSUE.
PHYS MED BIOL
1539 - 1558.
In this paper we show how to derive the mean and variance of the transilluminated signal obtained in models of light propagation in tissue, based both on a stochastic Monte Carlo method and on a deterministic diffusion approximation. The theoretical treatment of the Monte Carlo model applies only to integrated intensity measurements, whereas the diffusion approximation gives an estimator for the time-dependent case as well. We present results that show the accurate prediction of Monte Carlo statistics, and propose that the diffusion approximation is therefore a suitable mechanism for incorporating noise into modelling procedures.
|Title:||STATISTICAL BASIS FOR THE DETERMINATION OF OPTICAL PATHLENGTH IN TISSUE|
|Keywords:||MODEL, SCATTERING, ABSORPTION, LIGHT|
|UCL classification:||UCL > School of BEAMS > Faculty of Engineering Science > Computer Science|
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