UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Lung function and cognitive ability in a longitudinal birth cohort study

Richards, M; Strachan, D; Hardy, R; Kuh, D; Wadsworth, M; (2005) Lung function and cognitive ability in a longitudinal birth cohort study. Psychosomatic Medicine , 67 (4) pp. 602-608. 10.1097/01.psy.0000170337.51848.68.

Full text not available from this repository.

Abstract

Objective: The objective of this study was to examine the association between forced expiratory volume in 1 second (FEV 1 ) and cognitive ability in midlife in the normal population. Methods: Multiple regression was used to test associations between FEV 1 and cognitive function in 1778 men and women in the MRC National Survey of Health and Development, also known as the British 1946 birth cohort. Analyses were adjusted for sex, body size (birth weight, adult height, weight, and chest circumference), socioeconomic status, lifetime smoking, and a range of health indicators, including early respiratory vulnerability (infant lower respiratory infection, childhood asthma, and exposure to atmospheric pollution). Results: FEV 1 at 43 years was associated with slower psychomotor speed (peg placement) at the same age and with slower decline in psychomotor speed (letter search speed) from 43 to 53 years, independently of the previously mentioned potential confounders. These independent associations were not observed, however, for adult verbal ability, verbal memory, or rate of decline in memory, which were significantly explained by socioeconomic status and adolescent cognitive ability. In a subsequent analysis, adolescent cognition was positively associated with FEV 1 , although not with rate of decline in FEV 1 from 43 to 53 years, again independently of the previously mentioned confounders. Conclusions: Cognitive function and FEV 1 are positively associated across the life course. One possible explanation lies in the parallel action of endocrine, autonomic, and motor control systems on respiration and higher mental function. Because respiration and mental function are both associated with functional capacity and survival, this is a matter of potential clinical significance. Copyright © 2005 by the American Psychosomatic Society.

Type: Article
Title: Lung function and cognitive ability in a longitudinal birth cohort study
DOI: 10.1097/01.psy.0000170337.51848.68
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Education
UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education
UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education > IOE - Social Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
URI: http://discovery.ucl.ac.uk/id/eprint/55807
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item