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The effect of Cyclosporine A on cardiomyocytes differentiation

Paslaru, L; Davidson, S; Popescu, I; Morange, M; (2007) The effect of Cyclosporine A on cardiomyocytes differentiation. J CELL MOL MED , 11 (2) 369 - 371. 10.1111/j.1582-4934.2007.00029.x.

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Abstract

Cyclosporine A (CsA) is a powerful immunosuppressive drug which significantly improved the success of organ transplantation; however, the major limiting factors for the drug's clinical use are its long and short term adverse effects. The present study was conducted to examine, in a dose-dependent manner, in a model of cardiogenesis, the effect of CsA on cardiomyocytes differentiation.

Type: Article
Title: The effect of Cyclosporine A on cardiomyocytes differentiation
DOI: 10.1111/j.1582-4934.2007.00029.x
Keywords: Cyclosporine A, cardiomyocytes differentiation, HSP25 expression, cardiac actin expression, STEM-CELLS, PATHWAY, ACTIVATION, HSP25
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science > Pre-clinical and Fundamental Science
URI: http://discovery.ucl.ac.uk/id/eprint/54584
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