Wilkinson-Herbots, HM and Ettridge, R (2004) The effect of unequal migration rates on F-ST. THEOR POPUL BIOL , 66 (3) 185 - 197. 10.1016/j.tpb.2004.06.001.
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Using the structured coalescent model, it is shown that unequal migration rates between different pairs of subpopulations can increase the value of Wright's coefficient F-ST and its dependence on the mutation rate, and decrease the effective level of gene flow. Two specific models of population structure are considered: (i) an 'island model with barrier' where migration rates between subpopulations on the same side of the barrier are higher than migration rates between subpopulations on opposite sides of the barrier, and (ii) the two-dimensional stepping-stone model with unequal migration rates in the two dimensions of the model. (C) 2004 Elsevier Inc. All rights reserved.
|Title:||The effect of unequal migration rates on F-ST|
|Keywords:||coalescent, population structure, subpopulation differentiation, F-ST, effective level of gene flow, SUBDIVIDED POPULATIONS, GEOGRAPHICAL VARIATION, NEUTRAL MODELS, SPATIAL INHOMOGENEITIES, GENE FLOW, COALESCENCE TIMES, ISLAND MODEL, EQUILIBRIUM, EVOLUTION, DISTANCE|
|UCL classification:||UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Statistical Science|
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