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Workshop report on some new ideas about the treatment of systemic lupus erythematosus

Linnik, M; Staines, NA; Berden, J; Isenberg, DA; (2002) Workshop report on some new ideas about the treatment of systemic lupus erythematosus. LUPUS , 11 (12) 793 - 796. 10.1191/0961203302lu320oa.

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Abstract

Our increased understanding of the pathogenesis of systemic lupus erythematosus is leading to new ideas about its therapy. In this session of the workshop the use of UP 394 a B cell toleragen and the use of an anti-CD20 monoclonal antibody were discussed in some detail. Their rationale and early clinical results were reviewed; both have shown encouraging clinical and serological benefit. Definitive double-blind clinical trials are still, however, awaited. In addition, the intriguing notion of using a nasal instillation of a histone peptide was described and early work in an experimental model presented.

Type: Article
Title: Workshop report on some new ideas about the treatment of systemic lupus erythematosus
Location: UNIV COLL LONDON, LONDON, ENGLAND
DOI: 10.1191/0961203302lu320oa
Keywords: SLE, anti DNA antibody, histone peptide, ORAL TOLERANCE, CELLS, LJP-394, NEPHRITIS, ARTHRITIS
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation
URI: http://discovery.ucl.ac.uk/id/eprint/53676
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