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Physical and mental health: changes during menopause transition

Mishra, GD; Brown, WJ; Dobson, AJ; (2004) Physical and mental health: changes during menopause transition. Menopause digest , 16 pp. 26-29.

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Abstract

OBJECTIVE: To measure changes in physical and mental health in six groups of women defined by menopausal status or use of hormone replacement therapy (HRT). DESIGN: Longitudinal study with 2 years follow-up. PARTICIPANTS: Eight thousand six hundred and twenty three women participating in the Australian Longitudinal Study on Women's Health, aged 45-50 years in 1996. MAIN OUTCOME MEASURES: Changes in the eight dimensions of the Short Form General Health Survey (SF-36) adjusted for baseline scores, lifestyle, behavioural and demographic factors. RESULTS: At baseline, mean scores for five of the eight dimensions of the SF-36 were highest (indicating better state of health or well-being) in premenopausal women. There were declines (that is, worsening health) in the SF-36 dimensions in most groups of women. Declines were largest in physical functioning (adjusted mean change of -4.9, standard error (SE) 0.7) and physical role limitation (-5.7, SE: 1.3) in women who remained peri-menopausal throughout the study period and in women taking HRT at the time of either survey (physical functioning: -5.3 (0.7), role physical limitation: -7.5 (1.2)). They were smallest in women who remained pre-menopausal (physical functioning: -3.2 (0.7); role physical limitation: -2.1 (1.1)). CONCLUSIONS: Physical aspects of general health and well-being decline during the menopausal transition. Sensitive measures and careful analysis are needed to understand why these changes are worse for peri-menopausal women and those taking HRT

Type: Article
Title: Physical and mental health: changes during menopause transition
Additional information: DA - 20030611IS - 0962-9343 (Print)LA - engPT - Journal ArticlePT - Research Support, Non-U.S. Gov'tSB - IMCV: 61
Keywords: Aged, analysis, Australia, Female, Follow-Up Studies, gender, Health Status, Health Status Indicators, Hormone Replacement Therapy, Humans, Longitudinal Studies, Menopause, Mental Health, Middle Aged, Quality of Life, therapy, WOMEN, Women's Health
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: http://discovery.ucl.ac.uk/id/eprint/52954
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