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Protective efficacy of BCG vaccine against leprosy in southern Malawi.

Baker, D; Van-Tam, JN; Smith, SJ; (1993) Protective efficacy of BCG vaccine against leprosy in southern Malawi. Epidemiology and Infection , 111 (1) 21 - 25. 10.1017/S0950268800056636.

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Abstract

This paper describes a matched case-control study to determine the efficacy of BCG vaccine in preventing the occurrence of leprosy in southern Malaŵi, a previously unstudied area. The BCG immunization rate amongst 145 individuals with leprosy was 44.8%, compared to 62.5% in 290 matched controls. The protective efficacy of BCG vaccine against leprosy in this region was estimated to be 63.6%; smallpox immunization had no effect. These findings support the view that BCG vaccine should be considered as a control measure in areas where leprosy is endemic.

Type:Article
Title:Protective efficacy of BCG vaccine against leprosy in southern Malawi.
DOI:10.1017/S0950268800056636
Publisher version:http://dx.doi.org/10.1017/S0950268800056636
Language:English
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of)

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