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Pre-implantation basiliximab reduces incidence of early acute rejection in pediatric heart transplantation.

Grundy, N; Simmonds, J; Dawkins, H; Rees, P; Aurora, P; Burch, M; (2009) Pre-implantation basiliximab reduces incidence of early acute rejection in pediatric heart transplantation. J Heart Lung Transplant , 28 (12) 1279 - 1284. 10.1016/j.healun.2009.09.001.

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Abstract

Basiliximab is an anti-CD25 monoclonal antibody used as induction therapy in solid-organ transplantation. In this study we aim to determine whether pre-operative administration of basiliximab is beneficial in preventing early heart allograft rejection.

Type:Article
Title:Pre-implantation basiliximab reduces incidence of early acute rejection in pediatric heart transplantation.
Location:United States
DOI:10.1016/j.healun.2009.09.001
Language:English
Keywords:Acute Disease, Antibodies, Monoclonal, Biopsy, Child, Dose-Response Relationship, Drug, Female, Follow-Up Studies, Graft Rejection, Great Britain, Heart Transplantation, Humans, Immunosuppressive Agents, Incidence, Interleukin-2 Receptor alpha Subunit, Lymphocyte Count, Male, Preoperative Care, Prognosis, Recombinant Fusion Proteins, Retrospective Studies, Survival Rate, T-Lymphocytes, Time Factors, Transplantation, Homologous
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Child Health

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