UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Hepatic artery thrombosis after orthotopic liver transplantation: a review of nonsurgical causes.

Pastacaldi, S; Teixeira, R; Montalto, P; Rolles, K; Burroughs, AK; (2001) Hepatic artery thrombosis after orthotopic liver transplantation: a review of nonsurgical causes. Liver Transpl , 7 (2) 75 - 81. 10.1053/jlts.2001.22040.

Full text not available from this repository.

Abstract

Hepatic artery thrombosis (HAT) is one of the principal causes of morbidity and graft loss following liver transplantation. There are several risk factors for the development of HAT; technical aspects of the arterial anastomosis are important particularly for early thrombosis, but the improvement of surgical technique has lessened this problem. Apart from technical causes, other risk factors include a variety of conditions such as low donor/recipient age ratio, immunologic factors, clotting abnormalities, tobacco use, and infections. In particular, cytomegalovirus (CMV) infection of endothelial cells has been recently suggested as an infective cause of HAT, as it is known to be followed by a rapid procoagulant response. Thus, latent CMV in an allograft may become activated and promote or contribute to vascular thrombosis. This review evaluates these aspects, focusing on data relating CMV infection or viremia to HAT following liver transplantation.

Type:Article
Title:Hepatic artery thrombosis after orthotopic liver transplantation: a review of nonsurgical causes.
Location:United States
DOI:10.1053/jlts.2001.22040
Language:English
Keywords:Blood Coagulation Disorders, Hepatic Artery, Humans, Infection, Liver Transplantation, Organ Preservation, Risk Factors, Thrombosis, Time Factors

Archive Staff Only: edit this record