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Long-term mycophenolate mofetil monotherapy in combination with calcineurin inhibitors for chronic renal dysfunction after liver transplantation.

Raimondo, ML; Dagher, L; Papatheodoridis, GV; Rolando, N; Patch, DW; Davidson, BR; ... Burroughs, AK; + view all (2003) Long-term mycophenolate mofetil monotherapy in combination with calcineurin inhibitors for chronic renal dysfunction after liver transplantation. Transplantation , 75 (2) 186 - 190. 10.1097/01.TP.0000041702.31262.CD.

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Abstract

Calcineurin inhibitors (CNIs) are the first-line immunosuppressive agents administered after liver transplantation, but they cause renal impairment. Two recent randomized trials report cellular rejection and liver graft loss when mycophenolate mofetil (MMF) monotherapy was used as a renal-sparing agent. Our experience with MMF in the same setting but with longer follow-up is described.

Type:Article
Title:Long-term mycophenolate mofetil monotherapy in combination with calcineurin inhibitors for chronic renal dysfunction after liver transplantation.
Location:United States
DOI:10.1097/01.TP.0000041702.31262.CD
Language:English
Keywords:Adult, Aged, Calcineurin, Chronic Disease, Creatinine, Female, Graft Rejection, Humans, Immunosuppressive Agents, Kidney Diseases, Liver Transplantation, Male, Middle Aged, Mycophenolic Acid

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