Burroughs, AK; Malagelada, R; (1993) Potential indications for octreotide in gastroenterology: summary of workshop. Digestion , 54 Suppl 1 59 - 67.
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The potential therapeutic applications of somatostatin and octreotide in gastroenterology involve gut neuro-endocrine tumours, bleeding varices, bleeding peptic ulcers, gastro-intestinal fistulae, pancreatic fistulae, dumping syndrome, pancreatic pseudocysts, short bowel syndrome, acute pancreatitis, AIDS-related diarrhoea, intestinal subacute obstruction, idiopathic 'diarrhoea', irritable bowel syndrome and GIT tumours. Octreotide has a longer duration of action than somatostatin and can be administered by subcutaneous injection, thus making it suitable for long-term administration. Many of the potential gastro-intestinal indications require long-term administration and thus octreotide would be the agent of choice.
|Title:||Potential indications for octreotide in gastroenterology: summary of workshop.|
|Keywords:||Acquired Immunodeficiency Syndrome, Colonic Diseases, Functional, Diarrhea, Dumping Syndrome, Esophageal and Gastric Varices, Gastrointestinal Diseases, Gastrointestinal Hemorrhage, Humans, Octreotide, Pancreatic Diseases, Peptic Ulcer Hemorrhage, Short Bowel Syndrome, Time Factors|
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