UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

A comparison of transjugular and plugged-percutaneous liver biopsy in patients with impaired coagulation.

Sawyerr, AM; McCormick, PA; Tennyson, GS; Chin, J; Dick, R; Scheuer, PJ; Burroughs, AK; (1993) A comparison of transjugular and plugged-percutaneous liver biopsy in patients with impaired coagulation. J Hepatol , 17 (1) pp. 81-85.

Full text not available from this repository.

Abstract

Patients with liver disease frequently have impaired blood coagulation. The optimal method for liver biopsy in this situation is not established. To investigate this issue we randomised 117 patients with impaired blood coagulation, in whom liver biopsy was required, to receive either transjugular or plugged-percutaneous biopsy. Seventeen patients were excluded prior to biopsy and a protocol biopsy was performed in 100 patients (44 transjugular, 56 plugged-percutaneous). Liver tissue was obtained in 97 (42 transjugular, 55 plugged-percutaneous). Plugged-percutaneous liver biopsy was quicker and easier than transjugular liver biopsy and the biopsies obtained were significantly larger (12 +/- 5 mm vs. 6 +/- 4 mm; p < 0.001). However, 2 of 56 (3.5%) patients who received plugged-percutaneous biopsy had haemorrhage which required transfusion, while none of the 44 patients who received transjugular biopsy had haemorrhage (not significant). Both methods of liver biopsy were associated with a high success rate and a low incidence of complications. Plugged-percutaneous liver biopsy provides larger biopsies but may be associated with an increased risk of haemorrhage.

Type: Article
Title: A comparison of transjugular and plugged-percutaneous liver biopsy in patients with impaired coagulation.
Location: IRELAND
Keywords: Biopsy, Blood Coagulation Disorders, Female, Humans, Liver, Liver Cirrhosis, Liver Diseases, Male, Middle Aged, Platelet Count, Prothrombin Time
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)
URI: http://discovery.ucl.ac.uk/id/eprint/493545
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item