UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

ORTHOTOPIC LIVER-TRANSPLANTATION FOR CHRONIC HEPATITIS IN 2 PATIENTS WITH COMMON VARIABLE IMMUNODEFICIENCY

SMITH, MSH; WEBSTER, ADB; DHILLON, AP; DUSHEIKO, G; BOULTON, R; SAVAGE, K; ... BURROUGHS, AK; + view all (1995) ORTHOTOPIC LIVER-TRANSPLANTATION FOR CHRONIC HEPATITIS IN 2 PATIENTS WITH COMMON VARIABLE IMMUNODEFICIENCY. GASTROENTEROLOGY , 108 (3) 879 - 884.

Full text not available from this repository.

Abstract

Two patients with common variable immunodeficiency underwent orthotopic liver transplantation for chronic hepatitis, unequivocally caused by hepatitis C virus in one case. Although one patient had pneumonia 8 days after surgery and the other developed hepatic venular stenosis in the transplanted liver, both had a reasonably good quality of life for at least 15 months. However, both subsequently died of recurrent hepatitis C virus hepatitis or hemorrhage after splenectomy for hypersplenism. This shows that severe infection is not a major problem in patients with common variable immunodeficiency after liver transplantation provided they undergo prophylactic antimicrobial and immunoglobulin therapy. The longer term prognosis must be regarded as poor until more data are available following transplantation in similar patients.

Type:Article
Title:ORTHOTOPIC LIVER-TRANSPLANTATION FOR CHRONIC HEPATITIS IN 2 PATIENTS WITH COMMON VARIABLE IMMUNODEFICIENCY
Keywords:NON-B HEPATITIS, C VIRAL-INFECTION, INTRAVENOUS IMMUNOGLOBULIN, NON-A, HYPOGAMMAGLOBULINEMIA, DEFICIENCY, RECIPIENTS, GLOBULIN, DISEASE, THERAPY
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Wolfson Institute and Cancer Institute Administration > Cancer Institute > Research Department of Pathology

Archive Staff Only: edit this record