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Factors affecting plasma amino acid concentrations in control subjects.

Milsom, JP; Morgan, MY; Sherlock, S; (1979) Factors affecting plasma amino acid concentrations in control subjects. Metabolism , 28 (4) pp. 313-319.

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Abstract

Plasma amino acid concentrations were determined in groups of normal control subjects under fasting and postprandial conditions. Differences were observed that were found to be, to a considerable extent, sex-related. Fasting females had lower concentrations than fasting males of several amino acids, although postprandial differences in concentrations between the sexes were not significant. Under the dietary conditions normal for a British population, no significant diurnal variation of plasma amino acid concentrations was found. Reducing the dietary protein by 30% failed to affect plasma amino acid concentrations; however, increasing the dietary protein by 50% resulted in a significant increase in the plasma concentrations of several amino acids, and induced a significant degree of variation throughout the day in six, proline, half-cystine, methionine, valine, leucine, and isoleucine. The importance of these results with regard to the interpretation of population mean values and disease diagnosis is discussed.

Type: Article
Title: Factors affecting plasma amino acid concentrations in control subjects.
Location: United States
Keywords: Adolescent, Adult, Aged, Amino Acids, Circadian Rhythm, Cystine, Dietary Proteins, Eating, Fasting, Female, Humans, Isoleucine, Leucine, Male, Methionine, Middle Aged, Proline, Sex Factors, Valine
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inst for Liver and Digestive Hlth
URI: http://discovery.ucl.ac.uk/id/eprint/49309
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