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The role of <sup>99m</sup>Tc-depreotide in the management of neuroendocrine tumours

Shah, T; Kulakiene, I; Quigley, AM; Warbey, VS; Srirajaskanthan, R; Toumpanakis, C; Hochhauser, D; ... Caplin, ME; + view all (2008) The role of <sup>99m</sup>Tc-depreotide in the management of neuroendocrine tumours. Nuclear Medicine Communications , 29 (5) pp. 436-440.

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Abstract

In-pentetreotide scan (OctreoScan) is a widely available agent with high sensitivity for imaging neuroendocrine tumours. Negative In-pentetreotide poses diagnostic as well as therapeutic problems in terms of staging and consideration of targeted radionuclide therapy. To assess the role of 99m Tc-depreotide in patients with negative or weakly positive OctreoScan (Krenning score≤1; measured on a scale range 0-4). To determine the usefulness of 99m Tc-depreotide scintigraphy for highlighting lesions that may be missed by OctreoScan and/or CT/MRI imaging. Prospective analysis of 25 patients with neuroendocrine tumours, with negative or weakly positive In-pentetreotide scans, who were consecutively enrolled to undergo In-pentetreotide and 99m Tc-depreotide imaging. The results were compared with either CT or MRI scans. © 2008 Lippincott Williams & Wilkins, Inc.

Type: Article
Title: The role of <sup>99m</sup>Tc-depreotide in the management of neuroendocrine tumours
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Wolfson Institute and Cancer Institute Administration > Cancer Institute
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Wolfson Institute and Cancer Institute Administration > Cancer Institute > Research Department of Oncology
URI: http://discovery.ucl.ac.uk/id/eprint/47959
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