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The conduction system in hearts with pulmonary atresia and intact ventricular septum.

Ansari, A; Goltz, D; McCarthy, KP; Cook, A; Ho, SY; (2003) The conduction system in hearts with pulmonary atresia and intact ventricular septum. Ann Thorac Surg , 75 (5) pp. 1502-1505.

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Abstract

BACKGROUND: Although a regular course of the conduction system is anticipated in hearts with pulmonary atresia and intact ventricular septum (PAIVS), it has never been demonstrated anatomically. In view of one of the surgical options in repair being debulking of the right ventricular wall, it is important to establish the location of the major conduction pathways. METHODS: Four hearts belonging to fetuses aged 18, 20, 22, and 29 weeks were examined. Entire hearts were serially sectioned and step sections were stained. The sinus node and atrioventricular conduction bundles were identified and their locations described. RESULTS: The conduction system in hearts with PAIVS is similar to that in normal hearts, although there was a minor variation in one of them. This was a heart affected by Ebstein malformation of the tricuspid valve. In this case, the right bundle branch terminated abruptly soon after its origin. CONCLUSIONS: Confirmation of the regular course of the cardiac conduction system is important to the development of strategies for surgical repair of PAIVS.

Type: Article
Title: The conduction system in hearts with pulmonary atresia and intact ventricular septum.
Location: Netherlands
Keywords: Ebstein Anomaly, Fetus, Heart Conduction System, Heart Septum, Heart Ventricles, Humans, Pulmonary Atresia
UCL classification: UCL > Office of the President and Provost
UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
URI: http://discovery.ucl.ac.uk/id/eprint/47583
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