Sajid, MS; Desai, M; Haider, Z; Baker, DM; Hamilton, G; (2008) Endovascular aortic aneurysm repair (EVAR) has significantly lower perioperative mortality in comparison to open repair: A systematic review. Asian Journal of Surgery , 31 (3) 119 - 123.
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OBJECTIVE: The objective of this meta-analysis was to evaluate the effectiveness of endovascular abdominal aortic aneurysm repair (EVAR) in reducing inhospital mortality against open graft replacement for aortic aneurysm. METHODS: Generic terms including EVAR, endovascular aneurysm repair and aortic endografting were used to search a variety of electronic databases. Based on selection criteria, decisions regarding inclusion and exclusion of primary studies were made. RESULTS: A total of three randomized controlled trials on 1,468 patients were included. In the EVAR group, 12 of 759 (1.5%) patients died, compared to 33 of 709 (4.6%) patients who died in the open surgery group. In both the fixed and random effect models, EVAR was associated with statistically significantly lower perioperative mortality when compared to open surgical repair of aortic aneurysm. The risk ratio of 0.33 indicates that mortality is 3.3 times more likely in the open surgery group compared to the EVAR group. CONCLUSION: EVAR carries a. threefold lower risk of perioperative death in comparison to open repair of abdominal aortic aneurysm. This early advantage must be offset against the increased need for later re-intervention and probable equivalence of long-term outcome. In older and high operative risk patients, EVAR should be the treatment of choice
|Title:||Endovascular aortic aneurysm repair (EVAR) has significantly lower perioperative mortality in comparison to open repair: A systematic review|
|Additional information:||WoS ID: 000258136000004 Times Cited: 0ArticleEnglishSajid, M. SWorthing Dist Hosp, Washington Suite,North Wing, Brighton BN11 2DH, W Sussex, EnglandCited References Count: 10333EQELSEVIER SINGAPORE PTE LTD3 KILLINEY ROAD 08-01, WINSLAND HOUSE 1, SINGAPORE, 239519, SINGAPORESINGAPORE|
|Keywords:||aortic aneurysm, endograft, endovascular aneurysm repair, EVAR, TRIAL|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of)|
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