Bracco, C and Melchio, R and Sturlese, U and Pomero, F and Martini, G and Poggi, A and Cena, P and Severini, S and Castagna, E and Brignone, C and Serraino, C and Dutto, L and Veglio, F and Fenoglio, L (2010) Early stratification of patients with chest pain and suspected acute coronary syndrome in the Emergency Department. MINERVA MED , 101 (2) 73 - 80.
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Aim. The aim of this study was to investigate the accuracy of a critical pathway in the early stratification and management of patients with chest pain and suspected acute coronary syndrome (ACS) in the Emergency Department (ED).Methods. An observational study was performed-enrolling all patients with non-traumatic chest pain and suspected ACS who presented during a one-year period in the ED, where a critical pathway with five-level risk stratification, based on risk factors, characteristics of pain and ECG, was implemented. Patients were prospectively evaluated for rates of death, unstable angina, myocardial infarction or revascularization procedure occurring during admission or in the 30 days following discharge from the ED. Receiver-Operating Characteristics (ROC) curve was used to measure the accuracy of the stratification method.Results. Overall, 1 813 patients were enrolled: 475 patients (26.1%, 95% CI: 24.0-28.1) were admitted and 1 338 (73.8%, 95% CI: 71.7-75.8) were discharged. Main outcomes occurred in 233 (49.9%, 95% CI: 47.5-52.2) of patients admitted and in 6 (0.4%, 95% CI: 0.06-0.7) of those discharged. The risk stratification system showed a good accuracy with an AUC-ROC curve of 0.90 (95% CI: 0.88-0.93). A total of 1541 (85%) patients were managed according to critical pathway. Adverse events were significantly fewer in patients discharged according to pathway criteria than in those who were not (0.27% vs. 1.37%, difference: 1.1% CI 95%: 0.06-2.1), without significant increase of inappropriate admissions.Conclusion.. A critical pathway, based on clinical and ECG features, is a safe and accurate tool to stratify and manage the patients with non-traumatic chest pain and suspected ACS in the ED.
|Title:||Early stratification of patients with chest pain and suspected acute coronary syndrome in the Emergency Department|
|Keywords:||Chest pain, Acute coronary syndrome, Emergency department, Critical pathways, ST-SEGMENT ELEVATION, COMPREHENSIVE STRATEGY, MYOCARDIAL-INFARCTION, RISK SCORE, TASK-FORCE, MANAGEMENT, GUIDELINES, TRIAGE, TIMI|
|UCL classification:||UCL > School of BEAMS > Faculty of Engineering Science > Computer Science|
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