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DIVERSITY IN LOCALIZATION OF NITRIC-OXIDE SYNTHASE ANTIGEN AND NADPH-DIAPHORASE HISTOCHEMICAL STAINING IN SACRAL SOMATIC MOTOR-NEURONS OF THE CAT

PULLEN, AH; HUMPHREYS, P; (1995) DIVERSITY IN LOCALIZATION OF NITRIC-OXIDE SYNTHASE ANTIGEN AND NADPH-DIAPHORASE HISTOCHEMICAL STAINING IN SACRAL SOMATIC MOTOR-NEURONS OF THE CAT. NEUROSCI LETT , 196 (1-2) 33 - 36.

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Abstract

Nitric oxide synthase (NOS) immunoreactivity occurred in about 60% of ventromedial, ventrolateral, and sphincteric motoneurones in cat sacral spinal cord. Proportions of sacral motoneurones histochemically stained for NADPH-diaphorase, were similar, and equivalent in size to those immunoreactive for NOS, suggesting co-localisation of diaphorase and NOS. Double staining techniques revealed that NOS co-localised with NADPH-diaphorase in approximately 60% of sacral motoneurones. Some remaining motoneurones exhibited neither NOS nor NADPH-diaphorase, while others exhibited only NOS or NADPH-diaphorase, indicating phenotypic differences among sacral motoneurones.

Type:Article
Title:DIVERSITY IN LOCALIZATION OF NITRIC-OXIDE SYNTHASE ANTIGEN AND NADPH-DIAPHORASE HISTOCHEMICAL STAINING IN SACRAL SOMATIC MOTOR-NEURONS OF THE CAT
Keywords:ONUFS NUCLEUS, NITRIC OXIDE, NOS, MOTONEURON, ANAL SPHINCTER, ANAL-SPHINCTER MUSCLE, SPINAL-CORD, ONUF NUCLEUS, RAT, MOTONEURONS, IMMUNOHISTOCHEMISTRY, LOCALIZATION, AFFERENT, DISEASE, HRP
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology

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