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A life course approach to cognitive reserve: A model for cognitive aging and development?

Richards, M; Deary, IJ; (2005) A life course approach to cognitive reserve: A model for cognitive aging and development? ANN NEUROL , 58 (4) 617 - 622. 10.1002/ana.20637.

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Abstract

The concept of reserve in neuroscience maintains that there are aspects of brain structure and function that can buffer the effects of neuropathology such that the greater the reserve, the more severe the pathology must be to cause functional impairment. This article provides a concise overview of structural and functional approaches to reserve and shows how reserve may be conceived as the sum of its lifetime input. In this context, reserve therefore provides an empirical yet general model of cognitive aging and development.

Type: Article
Title: A life course approach to cognitive reserve: A model for cognitive aging and development?
DOI: 10.1002/ana.20637
Keywords: SCOTTISH MENTAL SURVEY, ALZHEIMERS-DISEASE, APOLIPOPROTEIN-E, BIRTH-WEIGHT, OLD-AGE, INTELLECTUAL-DEVELOPMENT, DEGENERATIVE CHANGES, HEAD CIRCUMFERENCE, ELDERLY SUBJECTS, EPISODIC MEMORY
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
URI: http://discovery.ucl.ac.uk/id/eprint/351562
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