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'Sterile' corneal infiltrates in contact lens wearers.

Bates, AK; Morris, RJ; Stapleton, F; Minassian, DC; Dart, JK; (1989) 'Sterile' corneal infiltrates in contact lens wearers. Eye (Lond) , 3 ( Pt pp. 803-810. 10.1038/eye.1989.124.

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Abstract

Ninety four patients with 'sterile' keratitis presenting consecutively over a nine month period to the Accident and Emergency Department of Moorfields Eye Hospital were studied. This condition was found to account for 0.49% of all new casualties. A significant association was found in these patients, compared with controls, with contact lens hygiene, particularly for daily wear soft contact lenses, and contact lens case contamination by bacteria suggesting that these may be important factors in the aetiology of 'sterile' keratitis. Compared to gas permeable hard contact lenses the relative risk of developing 'sterile' keratitis in our patients was found to be 2.3 times higher with extended wear soft contact lenses, 1.56 times higher with daily wear soft contact lenses and 0.509 with polymethylmethacrylate lenses (test of trend p-value less than 0.05). The results indicate that 'sterile' corneal infiltrates are related to contact lens hygiene and in part to contact lens case contamination by bacteria and also to the type of lens worn.

Type: Article
Title: 'Sterile' corneal infiltrates in contact lens wearers.
Location: England
DOI: 10.1038/eye.1989.124
Keywords: Adult, Analysis of Variance, Chi-Square Distribution, Chloramphenicol, Contact Lenses, Disinfection, Drug Therapy, Combination, Equipment Contamination, Female, Gentamicins, Humans, Hygiene, Keratitis, Male, Middle Aged, Prednisone, Prospective Studies
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: http://discovery.ucl.ac.uk/id/eprint/351143
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