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Survey of tangential field planning and dose distribution in the UK: background to the introduction of the quality assurance programme for the START trial in early breast cancer

Winfield, EA; Deighton, A; Venables, K; Hoskin, PJ; Aird, EGA; (2003) Survey of tangential field planning and dose distribution in the UK: background to the introduction of the quality assurance programme for the START trial in early breast cancer. British Journal of Radiology , 76 (904) pp. 254-259.

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Abstract

A background survey of UK breast radiotherapy techniques was performed prior to the introduction of the quality assurance programme for the Standardization of Radiotherapy (START) trial in breast cancer, a UK multicentre randomized trial of different dose fractionations for breast radiotherapy. Analysis of patient treatment plans was performed at this initial stage of the quality assurance programme to ensure eventual uniformity of treatment within the randomized trial and hence ensure reliable end results. As an integral part of this initial survey, three patient outlines of different size and shape were circulated between November 1997 and January 1998 to 56 UK radiotherapy centres. Dose distributions were produced according to the routine planning protocol of each department to provide information on treatment planning techniques. Criteria used for treatment plan production and the resultant dose distributions were analysed. The dose distributions varied between centres. Dose inhomogeneity of no more than 10% was achieved, oil the central axis, for all chest wall and medium breast size plans. The number of larger breast size distributions exceeding a 10% dose gradient across the treatment volume was 54% (26). Most centres in the UK determine the breast dose distribution by planning on a two-dimensional contour taken along the central plane of the breast. Variation in the breast contour either side of this central plane is not taken into account. Care with plan optimization by selecting the most appropriate beam parameters can lead to an improvement in breast dosimetry

Type: Article
Title: Survey of tangential field planning and dose distribution in the UK: background to the introduction of the quality assurance programme for the START trial in early breast cancer
Additional information: Journal English Article BRITISH INST RADIOLOGY 0 APR 680HG LONDON Winfield EA Royal Marsden Hosp, Dept Radiotherapy, Fulham Rd, London SW3 6JJ, England BRIT J RADIOL 36 PORTLAND PLACE, LONDON W1N 4AT, ENGLAND
Keywords: ACCOUNT, analysis, As, Axis, Breast, BREAST CANCER, breast dosimetry, BREAST-CANCER, British, cancer, Care, CRITERIA, distribution, Dosimetry, English, FIELD, gradient, IMPROVEMENT, INHOMOGENEITY, IRRADIATION, January, media, MULTICENTRE, November, NUMBER, oil, optimization, PARAMETER, PARAMETERS, Patient, planning, Protocol, QUALITY, Quality assurance, Radiology, Radiotherapy, randomized, RANDOMIZED TRIAL, RD, Result, SHAPE, size, standardization, Survey, technique, techniques, treatment, TRIAL, UK, uniformity, volume, WALL
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology
URI: http://discovery.ucl.ac.uk/id/eprint/31507
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