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Doses to fetal and maternal organs from intravenous (FeCl3)-Fe- 59 or (CoCl2)-Co-57

Saunders, M; Palmer, AM; Millard, RK; Preece, AW; (2003) Doses to fetal and maternal organs from intravenous (FeCl3)-Fe- 59 or (CoCl2)-Co-57. Radiation Protection Dosimetry , 106 (1) pp. 63-69.

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Abstract

Doses from intravenous intakes of Fe-59 or Co-57 chloride during pregnancy were estimated. Near term fetal organ doses were derived via the MIRDOSE3 newborn phantom, with mean dose/cumulated activity (S) values rescaled for compatibility with near term fetus whole body S. A detailed in vivo biodistribution database provided indications of residence times in important maternal and fetal organ S. Fe-59 doses to the fetus whole body front early to late pregnancy were 7-11 mGy MBq(-1) (8.5-14.3 mSv MBq(-1)). similar to that to the mother. Doses to near term fetal spleen (59 mGy MBq(-1)), liver (36), and red marrow (9) were similar or higher than to the mother. Co-57 doses to fetus whole body from early to late pregnancy were 0.7-3.3 mGy MBq(-1) (2.5-8.2 mSv MBq(-1)). similar or higher than to the mother. Doses to near term fetal small intestine (34 mGy MBq(-1)). liver (4.7) and red marrow (2.7) were similar or higher than to the mother

Type: Article
Title: Doses to fetal and maternal organs from intravenous (FeCl3)-Fe- 59 or (CoCl2)-Co-57
Additional information: Journal English Article NUCLEAR TECHNOLOGY PUBL 0 739AT ASHFORD Saunders M Univ Bristol, Div Oncol, Bristol, Avon, England RADIAT PROT DOSIM PO BOX 7, ASHFORD TN23 1YW, KENT, ENGLAND
Keywords: 711, activity, bodies, body, CHLORIDE, database, English, FE- 59, fetal, Fetus, in vivo, in-vivo, intestine, INTRAVENOUS, Kent, liver, M, MARROW, maternal, NEWBORN, nuclear, NUCLEAR-MEDICINE, PHANTOM, PLACENTAL-TRANSFER, PREGNANCIES, Pregnancy, RADIATION-DOSIMETRY, Radiopharmaceuticals, S, small, small intestine, SMALL-INTESTINE, Spleen, technology, TERM, TIME, VALUES, vivo
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology
URI: http://discovery.ucl.ac.uk/id/eprint/31164
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