UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Concordance for hypoplastic left heart syndrome in a monochorionic twin pregnancy.

Andrews, RE; Cook, AC; Yates, RWM; (2003) Concordance for hypoplastic left heart syndrome in a monochorionic twin pregnancy. Heart , 89 (4) , Article e13.

Full text not available from this repository.

Abstract

The risk of structural heart disease is significantly higher in twin pregnancies than in singleton pregnancies, but the concordance rate has been found to be relatively low, even in monochorionic pregnancies. This is the first report of a monochorionic twin pregnancy concordant for hypoplastic left heart syndrome (HLHS), the diagnosis having been made by fetal echocardiography at 15 weeks' gestation. The findings were confirmed at necropsy at 17 weeks' gestation, following termination of pregnancy. Both twins had mitral and aortic atresia, with severely hypoplastic aortic arches. This report adds weight to there being a genetic component to the cause of HLHS in some cases and illustrates how the findings from early fetal echocardiography with postmortem follow up can help to extend the understanding of the aetiology of this condition.

Type: Article
Title: Concordance for hypoplastic left heart syndrome in a monochorionic twin pregnancy.
Location: England
Keywords: Abortion, Induced, Adult, Diseases in Twins, Female, Humans, Hypoplastic Left Heart Syndrome, Pregnancy, Pregnancy, Multiple, Twins, Monozygotic
URI: http://discovery.ucl.ac.uk/id/eprint/29734
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item