Sadowski, H and Kolvin, I and Clemente, C and Tsiantis, J and Baharaki, S and Ba, G and Lee, C and Taylor, B (2002) Psychopathology in children from families with blood disorders: a cross-national study. European Child and Adolescent Psychiatry , 11 (4) 151 - 161.
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Background This study examines the prevalence of psychiatric disorders in affected and in unaffected siblings from families with haemophilia or beta-thalassaemia. Method Based on data derived from a cross-sectional and multi-centre study into the resilience of 115 families with blood disorders. Sociodemographic and developmental data were collected from the parent using a standardised and semi-structured interview, and medical data were elicited from,the attending clinician. The children's psychopathology was assessed with the Schedule for Affective Disorders and Schizophrenia (K-SADS). Results Children with beta-thalassaemia were twice as likely to receive a diagnosis of psychiatric disorder and more likely to show a higher degree of impairment of general functioning than haemophilic boys or unaffected children from families with blood disorders. Clinical severity of haemophilia or P- thalassaemia was not associated with significant differences in prevalence of child psychiatric disorders or impairment. Mothers' evaluation of their relationship with their child as 'less than easy' predicted psychopathology. Conclusions The high prevalence of psychopathology in children with P- thalassaemia reported in this study suggests that specific blood disorders have differential impact on affected children. This difference may be related to medical therapy advances in haemophilia so that haemophilic boys can lead an almost normal life
|Title:||Psychopathology in children from families with blood disorders: a cross-national study|
|Additional information:||Journal English Article DR DIETRICH STEINKOPFF VERLAG AUG 621WN DARMSTADT EUR CHILD ADOLESC PSYCHIATR PO BOX 10 04 62, D-64204 DARMSTADT, GERMANY|
|Keywords:||adjustment, adolescents, advances, As, BEHAVIOR, beta-thalassaemia, beta-Thalassemia, Blood, BOYS, Child, children, clinical, CLINICIAN, DEVELOPMENTAL, diagnosis, difference, DISORDER, Disorders, English, evaluation, families, families with blood disorders, family, functioning, Germany, Greece, haemophilia, health, HEMOPHILIA, HIV CRISIS, impact, IMPAIRMENT, INTERVIEW, K-SADS, LESS, LIFE, May, medical, MOTHERS, MULTICENTRE, parent, Prevalence, Psychiatric, psychiatric disorder, psychiatric disorders, PSYCHIATRIC-DISORDERS, PSYCHOPATHOLOGY, relationship, Result, SCHEDULE, Schizophrenia, Semi-Structured Interview, SEVERITY, Sibling, Siblings, thalassaemia, THERAPIES, therapy|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Child Health|
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