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The design of animal experiments: Reducing the use of animals in research through better experimental design

Festing, MFW; Overend, P; Gaines Das, R; Cortina-Borja, M; Berdoy, M; (2002) The design of animal experiments: Reducing the use of animals in research through better experimental design. [Book]. Laboratories Animals Limited: Vol.1. (1 ed.). The Royal Society of Medicine Press Limited: London.

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Abstract

Where there is no alternative to the use of experimental animals in biomedical research, it is important that experiments are well designed and correctly analysed in order to maximize the chance of getting scientifically valid results. Experiments that use too few animals may fail to pick up biologically important effects, while those that use too many or use them incorrectly may be subjecting them to unnecessary pain, distress or lasting harm. This book is aimed at all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively and/or to improve their ability to communicate with professional statisticians when designing more complex experiments. It covers many aspects of experimental design, such as choice of experimental animal, which are not considered by most statistics textbooks. Conversely, it does not cover the more advanced designs or statistical methods, so it should, ideally, be used in conjunction with more conventional statistics textbooks

Type: Book
Title: The design of animal experiments: Reducing the use of animals in research through better experimental design
ISBN: 1-85315-513-6
Additional information: Laboratory Animal Handbooks No. 14
Keywords: ABILITY, Animal, Animal Experiment, Animals, As, Biomedical Research, Book, chance, CHOICE, COMPLEX, COMPLEXES, design, DISTRESS, EB, effects, experimental, experiments, Handbook, Laboratories, laboratory, May, Methods, pain, Research, Result, STATISTICS, TBC, Use
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health > ICH Pop, Policy and Practice Prog
URI: http://discovery.ucl.ac.uk/id/eprint/28315
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