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Preimplantation genetic diagnosis: applications for molecular medicine.

Wells, D; Delhanty, JD; (2001) Preimplantation genetic diagnosis: applications for molecular medicine. Trends Mol Med , 7 (1) pp. 23-30.

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Abstract

Preimplantation genetic diagnosis is an alternative to prenatal diagnosis for the detection of genetic disorders. Tests are conducted on single cells biopsied from embryos before they are implanted, allowing the selection of unaffected embryos before a pregnancy has been established. Thus, the issue of pregnancy termination is circumvented. The use of preimplantation genetic diagnosis might have a significant impact on in vitro fertilization success rates as well as allowing the diagnosis of inherited disease.

Type: Article
Title: Preimplantation genetic diagnosis: applications for molecular medicine.
Location: England
Keywords: Abortion, Spontaneous, Chromosome Aberrations, Chromosome Disorders, DNA Mutational Analysis, Embryo Transfer, Ethics, Medical, Female, Fertilization in Vitro, Forecasting, Genetic Diseases, Inborn, Humans, In Situ Hybridization, Fluorescence, Micromanipulation, Mosaicism, Polymerase Chain Reaction, Pregnancy, Pregnancy Outcome, Preimplantation Diagnosis, Reproductive Techniques
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Inst for Women's Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Inst for Women's Health > Reproductive Health
URI: http://discovery.ucl.ac.uk/id/eprint/27648
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