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Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: Potent, non-peptidic blockers of the apamin-sensitive Ca2+-activated K+ channel

Rosa, JC; Galanakis, D; Piergentili, A; Bhandari, K; Ganellin, CR; Dunn, PM; Jenkinson, DH; (2000) Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: Potent, non-peptidic blockers of the apamin-sensitive Ca2+-activated K+ channel. JOURNAL OF MEDICINAL CHEMISTRY , 43 (3) pp. 420-431.

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Type: Article
Title: Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: Potent, non-peptidic blockers of the apamin-sensitive Ca2+-activated K+ channel
Keywords: Science & Technology, Life Sciences & Biomedicine, Chemistry, Medicinal, Pharmacology & Pharmacy, CHEMISTRY, MEDICINAL, SMALL-CONDUCTANCE, DEQUALINIUM ANALOGS, POTASSIUM PERMEABILITY, ENDOGENOUS EQUIVALENT, SKELETAL-MUSCLE, SCORPION TOXIN, LIGAND, CELLS, BRAIN, POLYPEPTIDES
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > School of BEAMS
UCL > School of BEAMS > Faculty of Maths and Physical Sciences
URI: http://discovery.ucl.ac.uk/id/eprint/25432
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