Protein structural topology: Automated analysis and diagrammatic representation.
897 - 904.
The topology of a protein structure is a highly simplified description of its fold including only the sequence of secondary structure elements, and their relative spatial positions and approximate orientations. This information can be embodied in a two-dimensional diagram of protein topology, called a TOPS cartoon. These cartoons are useful for the understanding of particular folds and making comparisons between folds. Here we describe a new algorithm for the production of TOPS cartoons, which is more robust than those previously available, and has a much higher success rate. This algorithm has been used to produce a database of protein topology cartoons that covers most of the data bank of known protein structures
|Title:||Protein structural topology: Automated analysis and diagrammatic representation|
|Additional information:||UI - 99226818 LA - Eng PT - JOURNAL ARTICLE DA - 19990714 IS -0961-8368 SB - M CY - UNITED STATES JC - BNW AA - Author EM -199909|
|Keywords:||Proteins, analysis, United States, Algorithms, bioinformatics, Chemistry, Physical, Computer Simulation, database, Genome, Methods, Models, Chemical, Models, Molecular, Protein Conformation, Protein Structure, Software, Structure|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of)|
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