UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

A whole genome association study in multiple sclerosis patients from north Portugal

Silva, BM; Thorlacius, T; Benediktsson, K; Pereira, C; Fossdal, R; Jonsson, HH; Silva, A; ... Jonasdottir, A; + view all (2003) A whole genome association study in multiple sclerosis patients from north Portugal. J NEUROIMMUNOL , 143 (1-2) 116 - 119. 10.1016/j.jneuroim.2003.08.024.

Full text not available from this repository.

Abstract

Genetic factors are known to influence susceptibility to multiple sclerosis (MS) but the genes involved are largely undefined. Here, we report an association study based on 200 patients and 200 controls from the Porto region in Portugal. A total of 3974 markers were successfully typed from which we have identified 46 markers showing evidence of association. When compared to a physical map three regions were found with two of these markers less than 1.5 Mb apart: chromosomes 6p21.3 (the MHC region), 6q14.1 and 7q34. (C) 2003 Elsevier B.V. All rights reserved.

Type: Article
Title: A whole genome association study in multiple sclerosis patients from north Portugal
DOI: 10.1016/j.jneuroim.2003.08.024
Keywords: multiple sclerosis, association, DNA pooling, genomic screen, linkage disequilibrium, GAMES, SCREEN, SUSCEPTIBILITY, FAMILIES, LINKAGE, LOCI, DNA
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
URI: http://discovery.ucl.ac.uk/id/eprint/21492
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item