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A portable instrument for measuring macular pigment with central fixation

Mellerio, J; Ahmadi-Lari, S; van Kuijk, F; Pauleikhoff, D; Bird, A; Marshall, J; (2002) A portable instrument for measuring macular pigment with central fixation. Current Eye Research , 25 (1) 37 - 47.

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PURPOSE: To evaluate the reliability and validity of a portable instrument for measuring macular pigment optical density. METHODS: The instrument is small, uses light emitting diodes as light sources and the principles of heterochromatic flicker photometry of comparing foveal and extra-foveal minimum flicker matches. It uses central fixation for the extra-foveal matches, which subjects found easier than eccentric fixation. Subjects with healthy eyes used the instrument to measure their pigment density in a number of eye clinics. RESULTS: The mean pigment density in 124 eyes in 124 individuals was 0.41 +/- 0.16 (mean +/- SD), there was no significant change with age but the density was less in females, those with light irides, smokers, subjects on diets low in precursor carotenoids and in those exposed to several hours of daylight every day or who used sun beds. CONCLUSIONS: The portable instrument gave valid and reliable data that confirmed published values for macular pigment. It was convenient to use in the clinic and has potential as a screening tool

Type: Article
Title: A portable instrument for measuring macular pigment with central fixation
Additional information: UI - 22405480 DA - 20030108 IS - 0271-3683 LA - eng PT - Journal Article PT - Validation Studies RN - 0 (Retinal Pigments) SB - IM
Keywords: adolescent, adult, age, Aged, Aged, 80 and over, analysis, As, BED, beds, Carotenoids, chemistry, Clinics, DENSITIES, DENSITY, Diagnostic Techniques, Ophthalmological, diet, Diets, Eye, Female, females, FIXATION, HEALTHY, IM, individuals, INSTRUMENT, instrumentation, LA, LESS, LIGHT, Low, Male, Methods, Middle Age, NUMBER, ophthalmology, optical, Photometry, pigments, PRINCIPLES, PUBLISHED, Reliability, Reproducibility of Results, Result, retina, Retinal Pigments, screening, SD, small, Support, Non-U.S.Gov't, TOOL, Use, VALIDATION, VALIDITY, VALUES
UCL classification: UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: http://discovery.ucl.ac.uk/id/eprint/191068
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