Hameed, M and Harridge, SDR and Goldspink, G (2002) Sarcopenia and hypertrophy: A role for insulin-like growth factor-1 in aged muscle? EXERC SPORT SCI REV , 30 (1) 15 - 19.
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Sarcopenia is the loss of muscle mass associated with the aging process. Although systemic or circulating growth hormone and insulin-like growth factor-1 levels fall as we age, this is likely to be of lesser importance in regard to muscle mass than the rule of locally produced insulin-like growth factor-Is generated in the muscle in response to exercise.
|Title:||Sarcopenia and hypertrophy: A role for insulin-like growth factor-1 in aged muscle?|
|Keywords:||muscle, strength, growth factors, aging, protein synthesis, MYOSIN HEAVY-CHAIN, SKELETAL-MUSCLE, GENE-EXPRESSION, IGF-I, PROTEIN, OLD, HORMONE, STRETCH, MEN|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Life Sciences|
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of)
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