Coulon, O; Hickman, SJ; Parker, GJ; Barker, GJ; Miller, DH; Arridge, SR; (2002) Quantification of spinal cord atrophy from magnetic resonance images via a B-spline active surface model. MAGN RESON MED , 47 (6) 1176 - 1185. 10.1002/mrm.10162.
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A method is presented that aims at segmenting and measuring the surface of the spinal cord from MR images in order to detect and quantify atrophy. A semiautomatic segmentation with very little intervention from an operator is proposed. It is based on the optimization of a B-spline active surface. The method allows for the computation of orthogonal cross-sections at any level along the cord, from which measurements are derived, such as cross-sectional area or curvature. An evaluation of the accuracy and reproducibility of the method is presented.
|Title:||Quantification of spinal cord atrophy from magnetic resonance images via a B-spline active surface model|
|Keywords:||active surface, atrophy, spinal cord, multiple sclerosis, MULTIPLE-SCLEROSIS, MRI, CONTOURS, ECHO|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > IoN - Neuroinflammation|
UCL > School of BEAMS > Faculty of Engineering Science > Computer Science
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