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FSP95, a testis-specific 95-kilodalton fibrous sheath antigen that undergoes tyrosine phosphorylation in capacitated human spermatozoa

Mandal, A; Naaby-Hansen, S; Wolkowicz, MJ; Klotz, K; Shetty, J; Retief, JD; ... Herr, JC; + view all (1999) FSP95, a testis-specific 95-kilodalton fibrous sheath antigen that undergoes tyrosine phosphorylation in capacitated human spermatozoa. Biology of Reproduction , 61 (5) 1184 - 1197.

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Abstract

Protein tyrosine phosphorylation has been associated with both capacitation and motility of mammalian sperm. During capacitation, human spermatozoa undergo tyrosine phosphorylation of a characteristic set of proteins, only one of which has thus far been cloned and localized. We report here the sequence of a fibrous sheath protein of 95 kDa (FSP95) that undergoes tyrosine phosphorylation during capacitation of human spermatozoa and has similarity to sperm A-kinase anchor proteins (AKAPs). FSP95 is both

Type:Article
Title:FSP95, a testis-specific 95-kilodalton fibrous sheath antigen that undergoes tyrosine phosphorylation in capacitated human spermatozoa
Additional information:UI - 99458739 LA - Eng RN - 0 (fibrous sheath protein 95) RN - 0 (DNA, Complementary) RN - 0 (Proteins) RN - 0 (Recombinant Proteins) RN - 55520-40-6 (Tyrosine) PT - JOURNAL ARTICLE ID -D43 TW/HD 00654/TW/FIC ID - HD U54 29099/HD/NICHD ID - P30 28934 DA - 19991206 IS - 0006-3363 SB - M CY - UNITED STATES JC - A3W AA - Author EM - 200002
Keywords:Antigens, Tyrosine, Phosphorylation, Spermatozoa, Proteins, DNA, recombinant, Recombinant Proteins, Id, United States, Amino Acid Sequence, analysis, biosynthesis, Blotting, Northern, Blotting, Southern, cell, Cloning, Molecular, DNA, Complementary, Escherichia coli, immunology, In Vitro, Infertility, isolation & purification, Male, mammalian, metabolism, Molecular Sequence Data, Molecular Weight, physiology, Sperm Capacitation, Support, U.S.Gov't, P.H.S., Testis, sperm
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of)

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