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Method for three-dimensional time-resolved optical tomography

Arridge, SR; Hebden, JC; Schweiger, M; Schmidt, FEW; Fry, ME; Hillman, EMC; Dehghani, H; (2000) Method for three-dimensional time-resolved optical tomography. International Journal of Imaging Systems and Technology , 11 (1) pp. 2-11. 10.1002/(SICI)1098-1098(2000)11:1<2::AID-IMA2>3.0.CO;2-J.

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We present an overview of time-resolved optical tomography together with the hardware and software methods that we have developed for a clinical instrument that implements this modality. The hardware is based on a multichannel photon-counting technique that records the histograms of photons time-of-flight through highly scattering and attenuating media. The software is based on a finite element model that is iteratively updated in order to minimize the difference between measured and modeled data. We have presented a first experimental reconstruction of a three-dimensional (3D) distribution of variable absorption and scattering coefficient, together with an ideal simulation of the same case.

Type: Article
Title: Method for three-dimensional time-resolved optical tomography
DOI: 10.1002/(SICI)1098-1098(2000)11:1<2::AID-IMA2>3.0.CO;2-J
URI: http://discovery.ucl.ac.uk/id/eprint/185300
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