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Acute liver failure: a review.

Khan, SA; Shah, N; Williams, R; Jalan, R; (2006) Acute liver failure: a review. Clin Liver Dis , 10 (2) 239-viii. 10.1016/j.cld.2006.05.010.

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Since publication of the first descriptions of acute liver failure (ALF) as a distinct clinical entity in the 1950's, the understanding of the pathophysiologic mechanisms involved and the management options have increased substantially. ALF still represents a major challenge for todays hepatologists, because it can rapidly lead to multiorgan failure and death that may be preventable with appropriate intervention. This article summarizes the basic patho-physiology underlying ALF, compares epidemiologic trends in the United States, the United Kingdom, and the Far East, and reviews prognostic markers and treatment options for ALF.

Type: Article
Title: Acute liver failure: a review.
Location: United States
DOI: 10.1016/j.cld.2006.05.010
Keywords: Far East, Humans, Liver Failure, Acute, United Kingdom, United States
URI: http://discovery.ucl.ac.uk/id/eprint/182549
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