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Acute liver failure: a review.

Khan, SA; Shah, N; Williams, R; Jalan, R; (2006) Acute liver failure: a review. Clin Liver Dis , 10 (2) 239 - viii. 10.1016/j.cld.2006.05.010.

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Since publication of the first descriptions of acute liver failure (ALF) as a distinct clinical entity in the 1950's, the understanding of the pathophysiologic mechanisms involved and the management options have increased substantially. ALF still represents a major challenge for todays hepatologists, because it can rapidly lead to multiorgan failure and death that may be preventable with appropriate intervention. This article summarizes the basic patho-physiology underlying ALF, compares epidemiologic trends in the United States, the United Kingdom, and the Far East, and reviews prognostic markers and treatment options for ALF.

Title:Acute liver failure: a review.
Location:United States
Keywords:Far East, Great Britain, Humans, Liver Failure, Acute, United States

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