Upile, T;
Jerjes, W;
Kafas, P;
Singh, SU;
Sudhoff, H;
Mahil, J;
Sandison, A;
(2009)
Ethical and technical considerations for the creation of cell lines in the head & neck and tissue harvesting for research and drug development (Part I): Techniques of tissue harvesting and propagation.
International Archives of Medicine
, 2
, Article 8. 10.1186/1755-7682-2-8.
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Abstract
Background: Although much has been published for the development of cell lines, these were lab based and developed for scientific technical staff. Objective of review: We present a simple and successful protocol for the development of cell lines and tissue harvesting for the clinical scientist. We also discuss the ethical implications of tissue retention and present a generic consent form. Conclusion: The advantages of hospital-based cell line creation are numerous. We can be more certain that cell lines are developed from the particular tissues of interest and accurate anatomical and appropriate clinico-pathological control tissues are also harvested. We can also be certain of less cell line cross contamination.
| Type: | Article |
|---|---|
| Title: | Ethical and technical considerations for the creation of cell lines in the head & neck and tissue harvesting for research and drug development (Part I): Techniques of tissue harvesting and propagation |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/1755-7682-2-8 |
| Publisher version: | http://dx.doi.org/10.1186/1755-7682-2-8 |
| Language: | English |
| Additional information: | © 2009 Upile et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | April, Cell lines, Development, Head, MS, Other, Research, Technique, Techniques |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > EDI MaxFac, Diagnostic, Med and Surg Sci |
| URI: | https://discovery.ucl.ac.uk/id/eprint/178980 |
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