Driver, J and Blankenburg, F and Bestmann, S and Vanduffel, W and Ruff, CC (2009) Concurrent brain-stimulation and neuroimaging for studies of cognition. TRENDS COGN SCI , 13 (7) 319 - 327. 10.1016/j.tics.2009.04.007.
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Neuroimaging can address activity across the entire brain in relation to cognition, but is typically correlative rather than causal. Brain stimulation can target a local brain area causally, but without revealing the entire network affected. Combining brain stimulation with concurrent neuroimaging allows a new causal approach to how interplay between extended networks of brain regions can support cognition. Brain stimulation does not affect only the targeted local region but also activity in remote interconnected regions. These remote effects depend on cognitive factors (e.g. task-condition), revealing dynamic changes in interplay between brain areas. We illustrate this with examples from top-down modulation of visual cortex, response-competition, interhemispheric rivalry and motor tasks; but the new approach should be applicable to many domains of cognition.
|Title:||Concurrent brain-stimulation and neuroimaging for studies of cognition|
|Keywords:||TRANSCRANIAL MAGNETIC STIMULATION, THETA-BURST-STIMULATION, FRONTAL EYE FIELD, VISUAL-CORTEX, TMS-FMRI, EVOKED-POTENTIALS, MOTOR CORTEX, POSTERIOR PARIETAL, PREFRONTAL CORTEX, SPATIAL ATTENTION|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Psychology and Language Sciences (Division of) > Institute of Cognitive Neuroscience|
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > Motor Neuroscience and Movement Disorders
UCL > School of Life and Medical Sciences > Faculty of Life Sciences
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