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Effects of dietary management of phenylketonuria on long-term cognitive outcome.

Channon, S; Goodman, G; Zlotowitz, S; Mockler, C; Lee, PJ; (2007) Effects of dietary management of phenylketonuria on long-term cognitive outcome. Arch Dis Child , 92 (3) 213 - 218. 10.1136/adc.2006.104786.

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Abstract

Phenylketonuria (PKU) is associated with dopaminergic depletion in the dorsolateral prefrontal cortex and abnormalities of myelination. Both mechanisms may lead to deficits in cognitive functioning. Studies of cognitive outcome in children treated with PKU at an early stage have suggested that there are benefits in remaining on diet into adolescence.

Type:Article
Title:Effects of dietary management of phenylketonuria on long-term cognitive outcome.
Location:England
DOI:10.1136/adc.2006.104786
Language:English
Additional information:PMCID: PMC2083434
Keywords:Adolescent, Adult, Age Factors, Aged, Analysis of Variance, Attention, Child, Child, Preschool, Cognition Disorders, Humans, Infant, Inhibition (Psychology), Memory, Middle Aged, Perception, Phenylketonurias, Psychomotor Performance
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Psychology and Language Sciences (Division of) > Experimental Psychology

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