Channon, S and Goodman, G and Zlotowitz, S and Mockler, C and Lee, PJ (2007) Effects of dietary management of phenylketonuria on long-term cognitive outcome. Arch Dis Child , 92 (3) 213 - 218. 10.1136/adc.2006.104786.
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Abstract
Phenylketonuria (PKU) is associated with dopaminergic depletion in the dorsolateral prefrontal cortex and abnormalities of myelination. Both mechanisms may lead to deficits in cognitive functioning. Studies of cognitive outcome in children treated with PKU at an early stage have suggested that there are benefits in remaining on diet into adolescence.
| Type: | Article |
|---|---|
| Title: | Effects of dietary management of phenylketonuria on long-term cognitive outcome. |
| Location: | England |
| DOI: | 10.1136/adc.2006.104786 |
| Language: | English |
| Additional information: | PMCID: PMC2083434 |
| Keywords: | Adolescent, Adult, Age Factors, Aged, Analysis of Variance, Attention, Child, Child, Preschool, Cognition Disorders, Humans, Infant, Inhibition (Psychology), Memory, Middle Aged, Perception, Phenylketonurias, Psychomotor Performance |
| UCL classification: | UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Psychology and Language Sciences (Division of) > Cognitive, Perceptual and Brain Sciences UCL > School of Life and Medical Sciences > Faculty of Life Sciences |
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