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Localized granulomatous reaction to a semi-permanent hyaluronic acid and acrylic hydrogel cosmetic filler

Sidwell, RU; Dhillon, AP; Butler, PEM; Rustin, MHA; (2004) Localized granulomatous reaction to a semi-permanent hyaluronic acid and acrylic hydrogel cosmetic filler. CLIN EXP DERMATOL , 29 (6) 630 - 632.

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Abstract

Dermalive, an injectable skin filler composed of a combination of synthetic hyaluronic acid and acrylic hydrogel particles was recently developed for soft tissue augmentation. Dermalive produces longer term results than temporary injectable fillers and is associated with a reportedly low incidence of adverse reactions. We describe a marked local reaction to the injection of Dermalive in the nasolabial fold developing within 4 months with histological confirmation of a granulomatous response. To our knowledge there has been only one previous report of a local granulomatous reaction to Dermalive.

Type:Article
Title:Localized granulomatous reaction to a semi-permanent hyaluronic acid and acrylic hydrogel cosmetic filler
Keywords:ADVERSE REACTIONS, COLLAGEN, SKIN
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of)
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Wolfson Institute and Cancer Institute Administration > Cancer Institute > Research Department of Pathology

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