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Composite tissue allotransplantation--a new era in plastic surgery?

Hettiaratchy, S; Randolph, MA; Petit, F; Lee, WP; Butler, PE; (2004) Composite tissue allotransplantation--a new era in plastic surgery? Br.J Plast.Surg. , 57 (5) 381 - 391.

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Abstract

Composite tissue allotransplantation (CTA) holds great potential for reconstructive surgery. The recent hand transplants have made this a clinical reality. However, concerns about CTA have divided the medical community. The current transplants require life-long immunosuppression, which could place the recipients at risk of serious complications. In addition despite potent immunosuppression, chronic rejection may still negate any early favourable results. This article will outline the clinical experience of CTA, the major problems of the technique and the potential solutions to these problems

Type:Article
Title:Composite tissue allotransplantation--a new era in plastic surgery?
Additional information:DA - 20040611IS - 0007-1226 (Print)LA - engPT - Journal ArticlePT - ReviewRN - 0 (Immunosuppressive Agents)SB - IM
Keywords:ERA, surgery, complications, Graft Rejection, Hand, Histocompatibility Testing, Humans, Immunosuppression, Immunosuppressive Agents, Knee Joint, Larynx, methods, Neurosurgery, Reconstructive Surgical Procedures, Risk, Risk Factors, Tendons, therapeutic use, transplantation, Transplantation, Homologous, Transplants, trends
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of)

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