Josephs, O; Henson, R; (1999) Event-related functional magnetic resonance imaging: modelling, inference and optimization. Philosophical Transactions of the Royal Society B: Biological Sciences , 354 (1387) pp.1215 - 1228.
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Event-related functional magnetic resonance imaging is a recent and popular technique for detecting haemodynamic responses to brief stimuli or events. However, the design of event-related experiments requires careful consideration of numerous issues of measurement, modelling and inference. Here we review these issues, with particular emphasis on the use of basis functions within a general linear modelling framework to model and make inferences about the haemodynamic response. With these models in mind, we then consider how the properties of functional magnetic resonance imaging data determine the optimal experimental design for a specific hypothesis, in terms of stimulus ordering and interstimulus interval. Finally, we illustrate various event-related models with examples from recent studies.
|Title:||Event-related functional magnetic resonance imaging: modelling, inference and optimization|
|Additional information:||Imported via OAI, 7:29:01 31st Aug 2007|
|Keywords:||Magnetic Resonance Imaging, magnetic resonance, imaging, modelling|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > Imaging Neuroscience|
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