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Modelling prostate gland motion for image-guided interventions

Hu, YP; Morgan, D; Ahmed, HU; Pendse, D; Sahu, M; Allen, C; Emberton, M; ... Barratt, D; + view all (2008) Modelling prostate gland motion for image-guided interventions. In: Bello, F and Edwards, PJ, (eds.) BIOMEDICAL SIMULATION, PROCEEDINGS. (pp. 79 - 88). SPRINGER-VERLAG BERLIN

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Abstract

A direct approach to using finite element analysis (FEA) to predict organ motion typically requires accurate boundary conditions, which can be difficult to measure during surgical interventions, and accurate estimates of soft-tissue properties, which vary significantly between patients. In this paper, we describe a method that combines FEA with a statistical approach to overcome these problems. We show how a patient-specific, statistical motion model (SMM) of the prostate gland, generated from FE simulations, can be used to predict the displacement field over the whole gland given sparse surface displacements. The method was validated using 3D transrectal ultrasound images of the prostates of five patients, acquired before and after expanding the balloon covering the ultrasound probe. The mean target registration error, calculated for anatomical landmarks within the gland, was 1.9mm.

Type: Proceedings paper
Title: Modelling prostate gland motion for image-guided interventions
Event: 4th International Symposium on Biomedical Simulation
Location: Imperial Coll, London, ENGLAND
Dates: 2008-07-07 - 2008-07-08
ISBN-13: 978-3-540-70520-8
Keywords: biomechanical modelling, finite element analysis, image-guided interventions, prostate cancer, ultrasound, statistical shape modelling, FINITE-ELEMENT-ANALYSIS, DEFORMABLE REGISTRATION, ACCURACY, CANCER
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > UCL Medical School
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: http://discovery.ucl.ac.uk/id/eprint/174364
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