UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Intestinal tuberculosis

Donoghue, HD; Holton, J; (2009) Intestinal tuberculosis. CURR OPIN INFECT DIS , 22 (5) 490 - 496. 10.1097/QCO.0b013e3283306712. Green open access

[img]
Preview
PDF - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
101Kb

Abstract

Purpose of reviewIntestinal tuberculosis (TB) is increasing due partly to the HIV pandemic. Its clinical presentation mimics inflammatory conditions such as Crohn's disease and malignancies, which are becoming more prevalent, so the diagnosis is problematic.Recent findingsGreater awareness of intestinal TB is needed, both in countries where TB is endemic and developed countries with immigrant populations. Some strains of Mycobacterium tuberculosis are associated with more extrapulmonary disease and greater dissemination, thereby exacerbating the rise in HIV-associated extrathoracic TB. Recent retrospective and prospective studies are leading to the development of diagnostic algorithms. A wide range of imaging techniques is available for sampling and diagnosis. New biochemical, immunological and molecular diagnostic methods are being developed but must be standardized and validated. Developments in drug delivery will facilitate oral therapy even in patients suffering from malabsorption.SummaryThere is an increasing consensus on the risk factors and clinical presentations of intestinal TB. Imaging techniques, coupled with fine needle biopsies, are useful aids to diagnosis, but most important is a greater awareness of the condition by clinicians.

Type:Article
Title:Intestinal tuberculosis
Open access status:An open access version is available from UCL Discovery
DOI:10.1097/QCO.0b013e3283306712
Keywords:abdomen, clinical presentation, diagnosis, Mycobacterium tuberculosis, treatment, FINE-NEEDLE-ASPIRATION, ABDOMINAL TUBERCULOSIS, MYCOBACTERIUM-TUBERCULOSIS, CROHNS-DISEASE, PERITONEAL TUBERCULOSIS, CASE SERIES, DIAGNOSIS, CHILDREN, LAPAROSCOPY, EXPERIENCE
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Infection and Immunity (Division of)

View download statistics for this item

Archive Staff Only: edit this record