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Image-based carotid flow reconstruction: a comparison between MRI and ultrasound

Glor, FP; Ariff, B; Hughes, AD; Crowe, LA; Verdonck, PR; Barratt, DC; ... Xu, XY; + view all (2004) Image-based carotid flow reconstruction: a comparison between MRI and ultrasound. PHYSIOL MEAS , 25 (6) 1495 - 1509. 10.1088/0967-3334/25/6/014.

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Abstract

Atherosclerosis is a major cause of morbidity and mortality. Its apparent link with wall shear stress (WSS) has led to considerable interest in the in vivo estimation of WSS. Determining WSS by combining medical images with computational fluid dynamics (CFD) simulations can be performed both with magnetic resonance imaging (MRI) and three-dimensional ultrasound (3DUS). This study compares predicted 3D flow patterns based on black blood MRI and 3DUS. Velocity fields in the carotid arteries of nine subjects have been reconstructed, and the haemodynamic wall parameters WSS, oscillatory shear index (OSI), WSS gradients (WSSG) and angle gradients (WSSAG) were compared between the two imaging techniques. There was a good qualitative agreement between results derived from MRI and 3DUS (average correlation strength above 0.60). The root mean square error between haemodynamic wall parameters was comparable to the range of the expected variability of each imaging technique (WSS: 0.411 N m(-2); OSI: 0.048; temporal WSSG: 150 N s(-1) m(-2); spatial WSSG: 2.29 N m(-3); WSSAG: 87.6 rad m(-1)). In conclusion, MRI and 3DUS are capable of providing haemodynamic parameters when combined with CFD, and the predictions are in most cases qualitatively and quantitatively similar. The relatively high cost of MRI and continuing improvement in ultrasound favour US to MRI for future haemodynamic studies of superficial arteries.

Type:Article
Title:Image-based carotid flow reconstruction: a comparison between MRI and ultrasound
DOI:10.1088/0967-3334/25/6/014
Keywords:Carotid bifurcation, MRI, atherosclerosis, 3D ultrasound, wall shear stress, haemodynamics, method comparison, COMPUTATIONAL FLUID-DYNAMICS, WALL SHEAR-STRESS, BLOOD-FLOW, ARTERY BIFURCATION, PULSATILE FLOW, STEADY FLOW, HEMODYNAMICS, MODELS, ATHEROSCLEROSIS, REPRODUCIBILITY
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Cardiometabolic Phenotyping Group
UCL > School of BEAMS > Faculty of Engineering Science > Medical Physics and Bioengineering

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