UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Influence of head position on carotid hemodynamics in young adults

Glor, FP; Ariff, B; Hughes, AD; Verdonck, PR; Barratt, DC; Augst, AD; Thom, SAM; (2004) Influence of head position on carotid hemodynamics in young adults. AM J PHYSIOL-HEART C , 287 (4) H1670 - H1681. 10.1152/ajpheart.01186.2003.

Full text not available from this repository.


Studies in adults have shown marked changes in geometry and relative positions of the carotid arteries when rotating the head. The aim of this study was to quantify the change in geometry and analyze its effect on carotid hemodynamics as a result of head rotation. The right carotid arteries of nine young adult subjects were investigated in supine position with straight and left turned head positions, respectively. The three-dimensional (3D) carotid geometry was reconstructed by using 3D ultrasound (3D US), and the carotid hemodynamics were calculated by combining 3D US with computational fluid dynamics. It was observed that cross-sectional areas and shapes did not change markedly with head rotation, but carotid vessel center lines altered with planarification of the common carotid artery as a main feature (P<0.05). Measured common carotid flow rates changed significantly at the individual level when the head was turned, but on the average, the change in mean common carotid flow rate was relatively small (0.37&PLUSMN;1.11 ml/s). The effect of the altered center lines and flow rates on the atherogenic nature of the carotid bifurcation was evaluated by using calculated hemodynamic wall parameters, such as wall shear stress (WSS) and oscillatory shear index (OSI). It was found that WSS and OSI patterns changed significantly with head rotation, but the variations were very subject dependent and could not have been predicted without assessing the altered geometry and flow of the carotid bifurcation for individual cases. This study suggests that there is a need for standardization of the choice of head position in the 3D US scan protocol, and that carotid stents and emboli diverters should be studied in different head positions.

Type: Article
Title: Influence of head position on carotid hemodynamics in young adults
DOI: 10.1152/ajpheart.01186.2003
Keywords: three-dimensional ultrasound, atherosclerosis, wall shear stress, computational fluid dynamics, MAGNETIC-RESONANCE IMAGES, BLOOD-FLOW, VULNERABLE PLAQUE, SHEAR-STRESS, WALL SHEAR, BIFURCATION, ARTERY, ATHEROSCLEROSIS, RECONSTRUCTION, ROTATION
URI: http://discovery.ucl.ac.uk/id/eprint/169700
Downloads since deposit
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item