Piccirillo, C and Perni, S and Gil-Thomas, J and Prokopovich, P and Wilson, M and Pratten, J and Parkin, IP (2009) Antimicrobial activity of methylene blue and toluidine blue O covalently bound to a modified silicone polymer surface. J MATER CHEM , 19 (34) 6167 - 6171. 10.1039/b905495b.
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Methylene Blue or Toluidine Blue O were covalently bound to an activated silicone polymer by means of an amide condensation reaction. UV-visible absorption spectra confirmed that the dye was surface bound. The new polymers with covalently attached dye display significant bactericidal activity against Escherichia coli and Staphylococcus epidermidis with a 99.999% reduction in viable bacteria after four minutes exposure to a low power laser.
|Title:||Antimicrobial activity of methylene blue and toluidine blue O covalently bound to a modified silicone polymer surface|
|Keywords:||LETHAL PHOTOSENSITIZATION, LIGHT|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > Microbial Diseases|
UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Chemistry
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