Cazares, A and Galman, JL and Crago, LG and Smith, MEB and Strafford, J and Rios-Solis, L and Lye, GJ and Dalby, PA and Hailes, HC (2010) Non-alpha-hydroxylated aldehydes with evolved transketolase enzymes. ORG BIOMOL CHEM , 8 (6) 1301 - 1309. 10.1039/b924144b.
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Abstract
Transketolase mutants previously identified for use with the non-phosphorylated aldehyde propanal have been explored with a series of linear and cyclic aliphatic aldehydes, and excellent stereoselectivities observed.
| Type: | Article |
|---|---|
| Title: | Non-alpha-hydroxylated aldehydes with evolved transketolase enzymes |
| DOI: | 10.1039/b924144b |
| Keywords: | ESCHERICHIA-COLI TRANSKETOLASE, ENZYMATIC THIAMIN CATALYSIS, CARBON BOND FORMATION, BIOCATALYTIC SYNTHESIS, SUBSTRATE-SPECIFICITY, XYLULOSE 5-PHOSPHATE, DIRECTED EVOLUTION, AMINO-ALCOHOLS, TRANSAMINASE, DIPHOSPHATE |
| UCL classification: | UCL > School of BEAMS > Faculty of Engineering Science > Biochemical Engineering UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Chemistry |
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