Bagan, J; Scully, C; Sabater, V; Jimenez, Y; (2009) Osteonecrosis of the jaws in patients treated with intravenous bisphosphonates (BRONJ): A concise update. ORAL ONCOL , 45 (7) 551 - 554. 10.1016/j.oraloncology.2009.01.002.
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Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a severe complication seen most frequently in patients on intravenous bisphosphonates treatment for malignant diseases. High potency bisphosphonates are generally implicated and risk factors also include dental extractions. Prevention is of paramount importance. Management is controversial but there is little evidence basis and the consensus is to be conservative. Recent advances in this area are summarised in this concise review. (C) 2009 Elsevier Ltd. All rights reserved.
|Title:||Osteonecrosis of the jaws in patients treated with intravenous bisphosphonates (BRONJ): A concise update|
|Keywords:||Osteonecrosis, Bisphosphonates, Cancer, Jaws, MULTIPLE-MYELOMA, RISK-FACTORS, HYPERBARIC-OXYGEN, ZOLEDRONIC ACID, THERAPY, CANCER, PREVENTION, PREDICTION, MANAGEMENT, FREQUENCY|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute|
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